Matsumoto (松本市 Matsumoto-shi?) is a Japanese city in the Chūbu region on the island of Honshu. It is a city located in Nagano Prefecture. Matsumoto is designated as a Special City. As of July 1, 2012, the city has an estimated population of 243,571 and a population density of 250 persons per km². The total area is 978.77 km².